Prof. Jumana Saleh from the College of Medicine of Sultan Qaboos University, Muscat, Oman will give a presentation about the regional fat distribution in obesity and associated metabolic risks and the implications of the role of the acylation stimulating protein.

According to Prof. Saleh, obesity is considered a major risk factor in the development of diabetes and cardiovascular disease that are leading causes of mortality in the Middle East.

Differences in fat distribution patterns in Obesity (i.e. visceral vs subcutaneous) determine metabolic risk. Visceral abdominal fat accumulation, which is common in males and postmenopausal women, is linked to insulin resistance, impaired glucose tolerance and dylipidemia. On the other hand, subcutanous fat accumulation (pear shape obesity) is more common in females with less metabolic risk. Fat storage differences are mainly attributed to reproductive hormone variations.

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